• Corkyskog@sh.itjust.works
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    20 hours ago

    So the researchers are planning trials where one person is vaccinated and then deliberately infected to see how their body copes.

    Umm… What? Excuse me, but when has this been legal?

    • how_we_burned@lemmy.zip
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      13 hours ago

      Umm… What? Excuse me, but when has this been legal?

      Well at this point in a vaccine development it’s already passed preclinical (animal testing toxicity) phase 0 and phase I trials (which determines their safety and dosing).

      They appear to be already at phase IIIb trial which is to test effectiveness with a group of people who are already at risk of exposure to the virus. Without a global pandemic this is axtually one the hardest and most expensive part of vaccine testing.

      One of the core reasons why the covid vaccines were so quick to be released was because there was a massive pool of people who were exposed to the virus (and who were willing to put there hand up to try it).

      We knew already that RNA vaccines were safe and weren’t deadly (as preclinical, phase 0 and phase 1 trials had already been done)

      Take the Ebola vaccines. These have taken decades to develop because outside of the outbreak we had 12 years ago very few people are exposed to Ebola. It was really hard to find at risk individuals.

      Also early Ebola vaccines used a live attenuated vaccine which had a one in a million chance that you get Ebola from the vaccine itself. So simply testing the vaccine could risk starting a epidemic

      That said the latest, FDA approved vaccine is a replication-competent recombinant vesicular stomatitis virus (VSV) vaccine (basically using another virus to deliver targeting data to your immune system.

    • Sam_Bass@lemmy.world
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      20 hours ago

      They’ve been doing that stuff to animals for decades. Time we all started sharing the load

    • Dozzi92@lemmy.world
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      20 hours ago

      I dunno, if the vaccine was “safe,” and it really comes down to will this stop me getting a cold, I’d take one for the team. Maybe not the flu or COVID, although COVID never affected me so maybe I wouldn’t be a good candidate.

      We just need an island of clones that we can test on, because clones aren’t real!