It doesn’t matter if the most upvoted comment is pro or against subject in discussion. All that matters is bolstering a comment that is minimally compatible with participant’s thinking and making it win against the opposite argument (competing and most voted one).
So it seems that the most satisfactory comment (for most readers) doesn’t really matter at all. What matters, before anything else, is visibility of an opinion that somewhat aligns with one’s thinking, rather than writing or finding the most corresponding comment for that subject, fully compatible with reader’s perception.
I never really did this on the bad place but if you browse new and fire off something snarky or heartfelt first it often becomes the top comment in my experience
Honestly, browsing by new is one of the fastest ways to become a recognizable power user. I actually did it for a while back on the bad place. After a while, you’re able to pretty quickly determine if a post is going to take off. Then you just drop a quick witty comment, and it’ll have thousands of upvotes and dozens of replies in a few hours.