This is wild. Mine would be raising a racket at 3am playing in the tubes. Is it relatively quiet?
This is wild. Mine would be raising a racket at 3am playing in the tubes. Is it relatively quiet?
The truth is, the biggest pharmaceutical companies aren’t really drug development companies at all: they’re marketing, lobbying, and litigation firms with patent portfolios. While Big Pharma holds vast portfolios of existing patents for prescription drugs, the innovation pipeline for new drugs actually has very little to do with Big Pharma. In reality, public sources — especially the NIH — fund the basic research that makes scientific breakthroughs. Then small, boutique biotech and pharmaceutical firms take that publicly generated knowledge and do the final stages of research, like running clinical trials, that get the drugs to market. The share of small companies in the supply of new drugs is huge, and it’s still growing. Fully two-thirds of new drugs now come from these small companies, up from one-third twenty years ago. It is not the research labs of Pfizer that are developing new drugs.
This is completely true. The majority of research, at least for life saving drugs and not baldness cures, takes place at universities and small research firms, much of it funded by the NIH. If the investigators are successful, they spin off a company or license the IP.
Big drug companies then step in, long after the initial “drug discovery” is done. They have captured the regulatory system and, yes, can fund and run Phase 3 trials with their deep pockets and armies of bureaucrats, but at that point they are acting more like record labels, extracting rent (loosely defined) from a convoluted regulatory and distribution system that they themselves had a hand in creating.
Fuck ‘em.
This is really cool.
I don’t know why this is such an appealing project, but it is. Adding an LED and a switch so it can be used as an emergency flashlight would be cool too.
Yep. I also think the ham-fisted way they are rolling this out is a projection of how they think the ‘libruls’ are brainwashing the kids.
Rather than educated people coming to educated conclusions on their own across vast segments of society, it is almost as if they think there is this secret committee of hooded Illuminati that generates Disney princess woke coloring books to turn little Billy-Bob away from Jesus, and the rest of the country just marches unthinkingly in lockstep with those orders. So of course, that is the playbook they want to follow.
I somehow feel this will backfire spectacularly. Younger kids can be dumb like the rest of us, but there is one thing they are exceptionally smart about: spotting and mocking lame-ass adults.
There is already little tolerance among (a lot of) younger folk for climate denialism and general right wing jackassery. Adding a cut-rate Donald Duck screeching about The Protocols of the Elders of Zion or how windmills are dangerous is just gonna’ cement the lameness for them. Now, if we could just do something about the grown-up idiots on Facebook, we’d be cooking.
Awesome game so far and remarkably well-polished due to the early access. My only real gripe is that the camera control is a little fiddly. It may be that I’m just not used to it, but a click and drag to rotate the camera would be chef’s kiss
Developing user cliques around fish names.
Nice. Is that PETG or PLA?
In a strange parallel to the current Russian political situation, can one at least hope that Meta drives a stake through the heart of the bird site before this effort implodes?
Probably not, I guess. If the Lizard King actually gets to the point that he poses a real threat, it is probably because he has eaten us first.
We note further that people who have isolated themselves from others or who live in solitude manifest this defect less frequently than individuals or groups of people inclined or condemned to sociability.
Heed my blue check mark.
Looking at comments on the bird site, I am pleasantly surprised at the number of submersible experts who are also Kremlinologists.
Death threats and actual harassment are serious business and are a matter for law enforcement, but a great strategy for dealing with the casual climate denier, anti-vaxxer, or Q idiot, is to just laugh at them. Not with, at. They cling to these ridiculous theories because at some level they want to feel in control and relevant in a scary world that they either won’t or can’t understand.
Treating them like kooks and refusing to get aggravated hits them the hardest because it tickles that suspicion that they really don’t get it. On the other hand, getting frustrated and trying to debate them about whether Hillary eats children just fuels the internal narrative that they are heroic truth warriors holding out in a hostile world.
Either way, kooks are gonna kook. You are not going to change their mind anyway, so why let it destroy your mental health.
I use mineral spirits, and have not had issues. Some folks recommend this stuff, But I have not tried it: https://www.tractorsupply.com/tsc/product/crown-psc-1000-parts-cleaner-5-gal