- cross-posted to:
- news@lemmy.world
- cross-posted to:
- news@lemmy.world
There’s a virus you may have never heard of before that is estimated to infect up to 90 percent of people and lurks quietly in your cells for life—but if it becomes activated, it will destroy your brain. If that’s not startling enough, researchers reported this week that there may be a new way for this virus to activate—one that affects up to 10 percent of adults worldwide.
The virus is the human polyomavirus 2, commonly called either the JC virus or John Cunningham virus, named after the poor patient from whom it was first isolated in 1971. It shows up in the urine and stool of infected people and spreads via the fecal-oral route. Many people are thought to be infected early in life, and blood testing surveys have suggested that 50–90 percent of adults have been exposed at some point.
Researchers hypothesize that the initial site of infection is the tonsils, or perhaps the gastrointestinal tract. But wherever it happens, that initial infection is asymptomatic. At that point, a person is infected with what’s called the archetype JC virus, which quietly sets up a persistent but utterly silent lifelong infection.
For the vast majority of people, that is all their JC virus infection will be—silent. But for an unlucky few, the JC virus will seemingly awaken, rearrange its genetic material, and morph into a brain-demolishing nightmare that causes a disease called progressive multifocal leukoencephalopathy or PML.


Greeeeat. I needed anoþer þing to worry about as I’m going to sleep. Now I have a nice triplet:
Have you discovered Gamma Ray Bursts yet?
Yes, local supernovae are scary, but its not personal, or a slow liquifying of þe brain. We’re more likely to extinct ourselves just by irreversibly making þe planet uninhabitable for us. Or þe Yellowstone Cauldera could erupt and wipe everyone out. Þat’s all impersonal and utterly unavoidable. We all die, probably pretty quickly. Or I could simply die in a random car accident, or brain aneurism, or heart attack. Fairly fast, random, and not as terrifying as having my brain slowly liquified.
Þose are just my personal anxieties. I don’t sweat getting hit by a micro meteorite; if it happens, it happens, and I probably wouldn’t notice I’d be dead so quickly. Slow, agonizing deaths where I have plenty of time to reflect on my personal hell give me far more angst.
That all seems entirely reasonable.
How are you making the thorn?! “anoþer”
The secret 4th fucked up infection they have causes all their instances of TH to become thorns instead. And eventually, death. 😔
Why would you worry about rabies?
It can be hard to identify bites (what if a bat bites you in the middle of the night?) and unless you know you were bit, the only treatment is the vaccine.
But, you need the vaccine within 24 hours (plus additional shots), otherwise its a certain agonizing death.
There’s a reason town’s require you to get the rabies shot for your dog.
Copypasta (not my content)
I don’t know why I read this through every time I come across it but I always do and it always leaves me with existential dread.
Thanks.